芹菜素 Apigenin
Antioxidant and chemopreventive
Apigenin is an antioxidant flavonoid. Has chemopreventive and antitumor properties. Induces apoptosis. Inhibits the proliferation of malignant tumor cells by G2/M arrest. Is a MAP-Kinase (MAPK/ERK) inhibitor. Inhibits hypoxia-inducible factor-1 (HIF-1) and vascular endothelial growth factor (VEGF) expression . Induces gastric relaxation in mouse stomach, mainly by suppressing Ca2+ influx through voltage-dependent calcium channels. Apigenin is a selective inhibitor of CK2. In WEHI 231 cells inhibition of CK2 by apigenin decreased the rate of IκBα turnover and nuclear levels of NF-κB (20 µM).
PRODUCT PROPERTIES
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Solubility:
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Soluble in diluted potassium hydroxyde or DMSO, slightly soluble in 100% ethanol (hot). Insoluble in water.
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Long Term Storage:
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Ambient
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Hazard:
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IRRITANT.
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MW:
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270.2
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CAS:
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520-36-5
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Formula:
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C15H10O5
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Purity:
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≥97% (TLC)
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Appearance:
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light yellow to slightly brown powder
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普華仕科技發(fā)展有限公司 --Puhuashi Technology Development Co., Ltd
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